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Immunolocalization of subnuclear compartments

StaffGiovanna Lattanzi, Stefano Squarzoni, Cristina Capanni, Elisabetta Mattioli, Vittoria Cenni, Rosalba Del Coco.


In recent years the use of optical microscopy associated to molecular biology has led to the identification of several functional domains that constitute the nucleus of mammalian cells. The analysis of the distribution of proteins in the nucleus is particularly interesting given that the space-time regulation of the biochemical processes in eukaryotes is obtained thanks to a high degree of compartmentalization. With this service we want to offer our expertise in support of research groups who work occasionally or who want to start studying proteins involved in genetic diseases that at least for a period of their life cycle staying in a district nuclear.

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