Sofia Francia

Istituto di Genetica Molecolare “Luigi Luca Cavalli-Sforza”
Via Abbiategrasso, 207 – 27100 PAVIA
tel: +39 0382 546325
fax: +39 0382 546370
E-mail: sofia.francia@igm.cnr.it

 


Pubblicazioni Recenti

2021

Mentegari E; Bertoletti F; Kissova M; Zucca E; Galli S; Tagliavini G; Garbelli A; Maffia A; Bione S; Ferrari E; d'Adda di Fagagna F; Francia S; Sabbioneda S; Chen LY; Lingner J; Bergoglio V; Hoffmann JS; Hubscher U; Crespan E; Maga G

A Role for Human DNA Polymerase lambda in Alternative Lengthening of Telomeres Journal Article

In: International journal of molecular sciences, 22 (5), pp. 2365, 2021.

Abstract | Links | BibTeX

Pessina F; Gioia U; Brandi O; Farina S; Ceccon M; Francia S; d'Adda di Fagagna F

DNA Damage Triggers a New Phase in Neurodegeneration Journal Article

In: Trends in genetics , 37 (4), pp. 337-354, 2021.

Abstract | Links | BibTeX

Cabrini M; Roncador M; Galbiati A; Cipolla L; Maffia A; Iannelli F; Sabbioneda S; d'Adda di Fagagna F; Francia S

DROSHA is recruited to DNA damage sites by the MRN complex to promote non-homologous end-joining Journal Article

In: Journal of cell science, 134 (6), pp. jcs249706, 2021.

Abstract | Links | BibTeX

Sharma S; Anand R; Zhang X; Francia S; Michelini F; Galbiati A; Williams H; Ronato DA; Masson JY; Rothenberg E; Cejka P; d'Adda di Fagagna F

MRE11-RAD50-NBS1 Complex Is Sufficient to Promote Transcription by RNA Polymerase II at Double-Strand Breaks by Melting DNA Ends. Journal Article

In: Cell reports, 34 (1), pp. 108565, 2021.

Abstract | Links | BibTeX

Farina S; Esposito F; Battistoni M; Biamonti G; Francia S

Post-Translational Modifications Modulate Proteinopathies of TDP-43, FUS and hnRNP-A/B in Amyotrophic Lateral Sclerosis. Journal Article

In: Frontiers in molecular biosciences, 8 , 2021.

Abstract | Links | BibTeX

2019

Gioia U; Francia S; Cabrini M; Brambillasca S; Michelini F; Jones-Weinert CW; d'Adda di Fagagna F

Pharmacological boost of DNA damage response and repair by enhanced biogenesis of DNA damage response RNAs. Journal Article

In: Scientific reports, 9 (1), pp. 6460, 2019.

Abstract | Links | BibTeX

Michelini F; Rossiello F; d'Adda di Fagagna F; Francia S

RNase A treatment and reconstitution with DNA damage response RNA in living cells as a tool to study the role of non-coding RNA in the formation of DNA damage response foci. Journal Article

In: Nature protocols, 14 (5), pp. 1489-1508, 2019.

Abstract | Links | BibTeX

2018

Michelini F; Jalihal AP; Francia S; Meers C; Neeb ZT; Rossiello F; Gioia U; Aguado J; Jones-Weinert C; Luke B; Biamonti G; Nowacki M; Storici F; Carninci P; Walter NG; d'Adda di Fagagna F

From "Cellular" RNA to "Smart" RNA: Multiple Roles of RNA in Genome Stability and Beyond. Journal Article

In: Chemical reviews, 118 (8), pp. 4365-4403, 2018.

Abstract | Links | BibTeX

2017

Iannelli F; Galbiati A; Capozzo I; Nguyen Q; Magnuson B; Michelini F; D'Alessandro G; Cabrini M; Roncador M; Francia S; Crosetto N; Ljungman M; Carninci P; d'Adda di Fagagna F

A damaged genome’s transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks Journal Article

In: Nature Communications, 8 , pp. 15656, 2017.

Abstract | Links | BibTeX

Pignataro D; Francia S; Zanetta F; Brenna G; Brandini S; Olivieri A; Torroni A; Biamonti G; Montecucco A

A missense MT-ND5 mutation in differentiated Parkinson Disease cytoplasmic hybrid induces ROS-dependent DNA Damage Response amplified by DROSHA. Journal Article

In: Scientific reports, 7 (1), pp. 9528, 2017.

Abstract | Links | BibTeX

Michelini F; Pitchiaya S; Vitelli V; Sharma S; Gioia U; Pessina F; Cabrini M; Wang Y; Capozzo I; Iannelli F; Matti V; Francia S; Shivashankar GV; Walter NG; d'Adda di Fagagna F

Comparison of computational methods for Hi-C data analysis. Journal Article

In: Nature cell biology, 19 (2), pp. 1400-1410, 2017.

Abstract | Links | BibTeX

Michelini F; Pitchiaya S; Vitelli V; Sharma S; Gioia U; Pessina F; Cabrini M; Wang Y; Capozzo I; Iannelli F; Matti V; Francia S; Shivashankar GV; Walter NG; d'Adda di Fagagna F

Damage-induced lncRNAs control the DNA damage response through interaction with DDRNAs at individual double-strand breaks. Journal Article

In: Nature cell biology, 19 (2), pp. 1400-1410, 2017.

Abstract | Links | BibTeX

Capozzo I; Iannelli F; Francia S; d'Adda di Fagagna F

Express or Repress? The Transcriptional Dilemma of Damaged Chromatin. Journal Article

In: FEBS journal, 284 (14), pp. 2133-2147, 2017.

Abstract | Links | BibTeX

Venkata Narayanan I; Paulsen MT; Bedi K; Berg N; Ljungman EA; Francia S; Veloso A; Magnuson B; d'Adda di Fagagna F; Wilson TE; Ljungman M

Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53. Journal Article

In: Scientific reports, 7 (1), pp. 43598, 2017.

Abstract | Links | BibTeX

2016

Francia S; Cabrini M; Matti V; Oldani A; d'Adda di Fagagna F

DICER, DROSHA and DNA damage response RNAs are necessary for the secondary recruitment of DNA damage response factors. Journal Article

In: Journal of Cell Science, 129 , pp. 1468-1476, 2016.

Abstract | Links | BibTeX