Monica Rapino

Istituto di Genetica Molecolare “Luigi Luca Cavalli-Sforza”

c/o Dipartimento di Medicina e Scienze dell’Invecchiamento – Università di Chieti

Via Dei Vestini 31, 66013 Chieti Scalo (CH)

Tel. 0871 3554522

Email: monica.rapino@igm.cnr.it


Curriculum Vitae – Download

Elenco Completo Pubblicazioni – Download


Attività di Ricerca:

Valutazione degli effetti neuroprotettivi e antitumorali di sostanze naturali o di nuova sintesi su cellule primarie, linee cellulari e co-colture.

Valutazione della risposta cellulare ai biomateriali.

 

Competenze

  1. Colture cellulari: in sospensione e in monostrato.
  2. Tecniche di base per la Microscopia Elettronica.
  3. Tecniche di base di immunocitochimica per la Microscopia Ottica ed Elettronica.
  4. Tecniche biochimiche:
    • Preparazione omogenati cellulari
    • Estrazione nuclei
    • Elettroforesi di proteine, DNA e RNA
    • Western blotting
    • E.L.I.S.A.
    • Analisi MTT
    • Analisi LDH
  5. Apparecchiature utilizzate:
    • Centrifughe
    • Citocentrifuga
    • Spettrofotometro per dosaggio proteine, DNA e RNA
    • Apparecchiature per elettroforesi
    • Strumentazione per colture cellulari
    • Microscopio ottico (a luce diretta e rovesciato) e a fluorescenza


Progetti di ricerca

FAR 2019, responsabile prof.ssa Cataldi: “Caratterizzazione biologica di materiali innovativi integrati con nanosistemi ibridi per la rigenerazione dei tessuti e relative applicazioni in campo biomedico”.



Pubblicazioni recenti

2024

Balaha M; Cataldi A; Ammazzalorso A; Cacciatore I; De Filippis B; Di Stefano A; Maccallini C; Rapino M; Korona-Glowniak I; Przekora A; di Giacomo V

CAPE derivatives: Multifaceted agents for chronic wound healing Journal Article

In: Archiv der Pharmazie, 2024.

Abstract | Links | BibTeX

2023

Barbaraci C; di Giacomo V; Maruca A; Patamia V; Rocca R; Dichiara M; Di Rienzo A; Cacciatore I; Cataldi A; Balaha M; Rapino M; Zagni C; Zampieri D; Pasquinucci L; Parenti C; Amata E; Rescifina A; Alcaro S; Marrazzo A.

Discovery of first novel sigma/HDACi dual-ligands with a potent in vitro antiproliferative activity Journal Article

In: Bioorganic chemistry, vol. 140, pp. 106794, 2023.

Abstract | Links | BibTeX

2022

Panara V; Chiacchiaretta P; Rapino M; Maruotti V; Parenti M; Piccirilli E; Pizzi AD; Caulo M

Dynamic susceptibility MR perfusion imaging of the brain: not a question of contrast agent molarity Journal Article

In: Neuroradiology, vol. 64, iss. 4, pp. 685-692, 2022.

Abstract | Links | BibTeX

Zengin G; Ak G; Ceylan R; Uysal S; Llorent-Martínez E; Di Simone SC; Rapino M; Acquaviva A; Libero ML; Chiavaroli A; Recinella L; Leone S; Brunetti L; Cataldi A; Orlando G; Menghini L; Ferrante C; Balaha M; di Giacomo V

Novel Perceptions on Chemical Profile and Biopharmaceutical Properties of Mentha spicata Extracts: Adding Missing Pieces to the Scientific Puzzle Journal Article

In: Plants (Basel), vol. 11, iss. 2, pp. 233, 2022.

Abstract | Links | BibTeX

2021

di Giacomo V; Recinella L; Chiavaroli A; Orlando G; Cataldi A; Rapino M; Di Valerio V; Politi M; Antolini MD; Acquaviva A; Bacchin F; Di Mascio M; Leone S; Brunetti L; Menghini L; Carradori S; Zengin G; Ak G; Ferrante C

Metabolomic Profile and Antioxidant/Anti-Inflammatory Effects of Industrial Hemp Water Extract in Fibroblasts, Keratinocytes and Isolated Mouse Skin Specimens Journal Article

In: Antioxidants (Basel), vol. 10, no 1, pp. 44, 2021.

Abstract | Links | BibTeX

Chiavaroli A; Balaha M; Acquaviva A; Ferrante C; Cataldi A; Menghini L; Rapino M; Orlando G; Brunetti L; Leone S; Recinella L; di Giacomo V

Phenolic Characterization and Neuroprotective Properties of Grape Pomace Extracts Journal Article

In: Molecules, vol. 26, no 20, pp. 6216, 2021.

Abstract | Links | BibTeX

Gallorini M; Rapino M; Schweikl H; Cataldi A; Amoroso R; Maccallini C

Selective Inhibitors of the Inducible Nitric Oxide Synthase as Modulators of Cell Responses in LPS-Stimulated Human Monocytes Journal Article

In: Molecules, vol. 26, no 15, pp. 4419, 2021.

Abstract | Links | BibTeX

2020

di Giacomo V; Chiavaroli A; Recinella L; Orlando G; Cataldi A; Rapino M; Di Valerio V; Ronci M; Leone S; Brunetti L; Menghini L; Zengin G; Ak G; Abdallah HH; Ferrante C

Antioxidant and Neuroprotective Effects Induced by Cannabidiol and Cannabigerol in Rat CTX-TNA2 Astrocytes and Isolated Cortexes Journal Article

In: International journal of molecular sciences, vol. 21, no 10, pp. 3575, 2020.

Abstract | Links | BibTeX

Recinella L; Chiavaroli A; Ronci M; Menghini L; Brunetti L; Leone S; Tirillini B; Angelini P; Covino S; Venanzoni R; Zengin G; Di Simone S; Ciferri MC; di Giacomo V; Cataldi A; Rapino M; Valerio VD; Orlando G; Ferrante C

Multidirectional Pharma-Toxicological Study on Harpagophytum procumbens DC. ex Meisn.: An IBD-Focused Investigation. Journal Article

In: Antioxidants, vol. 9, no 2, pp. e168, 2020.

Abstract | Links | BibTeX

di Giacomo V; Chiavaroli A; Orlando G; Cataldi A; Rapino M; Di Valerio V; Leone S; Brunetti L; Menghini L; Recinella L; Ferrante C

Neuroprotective and Neuromodulatory Effects Induced by Cannabidiol and Cannabigerol in Rat Hypo-E22 cells and Isolated Hypothalamus. Journal Article

In: Antioxidants, vol. 9, no 1, 2020.

Abstract | Links | BibTeX

di Giacomo V; Chiavaroli A; Orlando G; Cataldi A; Rapino M; Di Valerio V; Leone S; Brunetti L; Menghini L; Recinella L; Ferrante C

Neuroprotective and Neuromodulatory Effects Induced by Cannabidiol and Cannabigerol in Rat Hypo-E22 cells and Isolated Hypothalamus. Journal Article

In: Antioxidants, vol. 9, no 1, pp. e71, 2020.

Abstract | Links | BibTeX

2019

Rapino M; Di Valerio V; Zara S; Gallorini M; Marconi GD; Sancilio S; Marsich E; Ghinassi B; di Giacomo V; Cataldi A

Chitlac-coated Thermosets Enhance Osteogenesis and Angiogenesis in a Co-culture of Dental Pulp Stem Cells and Endothelial Cells. Journal Article

In: Nanomaterials, vol. 9, no 7, pp. pii: E928, 2019.

Abstract | Links | BibTeX

di Giacomo V; Ferrante C; Ronci M; Cataldi A; Di Valerio V; Rapino M; Recinella L; Chiavaroli A; Leone S; Vladimir-Knežević S; Kindl M; Brunetti L; Menghini L; Orlando G

Multiple pharmacological and toxicological investigations on Tanacetum parthenium and Salix alba extracts: Focus on potential application as anti-migraine agents. Journal Article

In: Food and chemical toxicology, vol. 133, pp. 110783, 2019.

Abstract | Links | BibTeX

2017

Pacella S; Fiorito J; Cacciatore I; di Giacomo V; Patruno A; Rapino M; Di Stefano A; Marinelli L; Fornasari E; Cataldi A; Prezzavento O; Marrazzo A

Effect of MRJF4 on C6 Glioma Cells Proliferation and Migration. Journal Article

In: Central nervous system agents in medicinal chemistry, vol. 17, no 2, pp. 129-134, 2017.

Abstract | Links | BibTeX

2016

Gallorini M; di Giacomo V; Di Valerio V; Rapino M; Bosco D; Travan A; Di Giulio M; Di Pietro R; Paoletti S; Cataldi A; Sancilio S

Cell-protection mechanism through autophagy in HGFs/S. mitis co-culture treated with Chitlac-nAg. Journal Article

In: Journal of Materials Science. Materials in Medicine., vol. 27, no 12, pp. 186, 2016.

Abstract | Links | BibTeX

Di Nisio C; Sancilio S; Di Giacomo V; Rapino M; Sancillo L; Genovesi D; Di Siena A; Rana RA; Cataldi A; Di Pietro R

Involvement of cyclic-nucleotide response element-binding family members in the radiation response of Ramos B lymphoma cells. Journal Article

In: International Journal of Oncology, vol. 48, no 1, 2016.

Abstract | Links | BibTeX

2015

Di Nisio C; De Colli M; di Giacomo V; Rapino M; Di Valerio V; Marconi GD; Gallorini M; Di Giulio M; Cataldi A; Zara S

A dual role for beta1 integrin in an in vitro Streptococcus mitis/human gingival fibroblasts co-culture model in response to TEGDMA. Journal Article

In: International Endodontic Journal, vol. 48, no 9, 2015.

Abstract | Links | BibTeX

Di Giacomo V; Di Valerio V; Rapino M; Bosco D; Cacciatore I; Ciulla M; Marrazzo A; Fiorito J; Di Stefano A; Cataldi A

MRJF4, a novel histone deacetylase inhibitor, induces p21 mediated autophagy in PC3 prostate cancer cells. Journal Article

In: Cellular and Molecular Biology (Noisy-le-Grand, France) , vol. 61, no 3, 2015.

Abstract | Links | BibTeX

Grande R; Pacella S; Di Giulio M; Rapino M; Di Valerio V; Cellini L; Cataldi A

NF-kB mediated down-regulation of collagen synthesis upon HEMA (2-hydroxyethyl methacrylate) treatment of primary human gingival fibroblast/Streptococcus mutans co-cultured cells. Journal Article

In: Clinical Oral Investigations, vol. 19, no 4, 2015.

Abstract | Links | BibTeX