Cristina Capanni


Istituto di Genetica Molecolare “Luigi Luca Cavalli-Sforza” – Sede di Bologna
c/o Istituto Ortopedico Rizzoli -via di Barbiano 1/10
40136 Bologna 
Phone: +39 051 636856

E-mail: ccapanni@area.cnr.bo.it

Curriculum Vitae – Download

Elenco completo delle pubblicazioni – Download


Attività di ricerca

Studio delle lamine, emerina e BAF (Barrier to Autointegration Factor) nell’organizzazione della cromatina in risposta alle condizioni di stress e durante il differenziamento del tessuto osseo, muscolare e adiposo sia in modelli normali che patologici, in particolare in campioni biologici provenienti da pazienti laminopatici caratterizzati da forme di distrofia muscolare, lipodistrofia e invecchiamento precoce.


Pubblicazioni Recenti

2021

Piazzi M; Kojic S; Capanni C; Stamenkovic N; Bavelloni A; Marin O; Lattanzi G; Blalock WL; Cenni V

Ectopic Expression of Ankrd2 Affects Proliferation, Motility and Clonogenic Potential of Human Osteosarcoma Cells. Journal Article

Cancers (Basel), 13 (2), pp. e174, 2021.

Abstract | Links | BibTeX

Squarzoni S; Schena E; Sabatelli P; Mattioli E; Capanni C; Cenni V; D'Apice MR; Andrenacci D; Sarli G; Pellegrino V; Festa A; Baruffaldi F and Storci G; Bonafè M; Barboni C; Sanapo M; Zaghini A; Lattanzi G

Interleukin-6 neutralization ameliorates symptoms in prematurely aged mice. Journal Article

Aging Cell, 20 (1), pp. e13285, 2021.

Abstract | Links | BibTeX

Costa R; Rodia MT; Zini N; Pegoraro V; Marozzo R; Capanni C; Angelini C; Lattanzi G; Santi S; Cenacchi G

Morphological study of TNPO3 and SRSF1 interaction during myogenesis by combining confocal, structured illumination and electron microscopy analysis. Journal Article

Molecular and cellular biochemistry, 476 (4), pp. 1797-1811, 2021.

Abstract | Links | BibTeX

2020

Cenni V; Squarzoni S; Loi M; Mattioli E; Lattanzi G; Capanni C

Emerin Phosphorylation during the Early Phase of the Oxidative Stress Response Influences Emerin-BAF Interaction and BAF Nuclear Localization Journal Article

Cells, 9 (6), pp. 1415, 2020.

Abstract | Links | BibTeX

Cenni V; Capanni C; Mattioli E; Schena E; Squarzoni S; Bacalini MG; Garagnani P; Salvioli S; Franceschi C; Lattanzi G

Lamin A Involvement in Ageing Processes Journal Article

Ageing research reviews, 62 , pp. 101073, 2020.

Abstract | Links | BibTeX

Zaghini A; Sarli G; Barboni C; Sanapo M; Pellegrino V; Diana A; Linta N; Rambaldi J; D'Apice MR; Murdocca M; Baleani M; Baruffaldi F; Fognani R; Mecca R; Festa A; Papparella S; Paciello O; Prisco F; Capanni C; Loi M; Schena E; Lattanzi G; Squarzoni S

Long term breeding of the Lmna G609G progeric mouse: Characterization of homozygous and heterozygous models. Journal Article

Experimental gerontology, 130 , pp. 110784, 2020.

Abstract | Links | BibTeX

Zaghini A; Sarli G; Barboni C; Sanapo M; Pellegrino V; Diana A; Linta N; Rambaldi J; D'Apice MR; Murdocca M; Baleani M; Baruffaldi F; Fognani R; Mecca R; Festa A; Papparella S; Paciello O; Prisco F; Capanni C; Loi M; Schena E; Lattanzi G; Squarzoni S

Long term breeding of the Lmna G609G progeric mouse: Characterization of homozygous and heterozygous models. Journal Article

Experimental gerontology, 130 , pp. 110784, 2020.

Abstract | Links | BibTeX

Santi S; Cenni V; Capanni C; Lattanzi G; Mattioli E

PCAF Involvement in Lamin A/C-HDAC2 Interplay during the Early Phase of Muscle Differentiation Journal Article

Cells, 9 (7), pp. E1735, 2020.

Abstract | Links | BibTeX

2019

Pellegrini C; Columbaro M; Schena E; Prencipe S; Andrenacci D; Iozzo P; Angela Guzzardi M; Capanni C; Mattioli E; Loi M; Araujo-Vilar D; Squarzoni S; Cinti S; Morselli P; Giorgetti A; Zanotti L; Gambineri A; Lattanzi G

Altered adipocyte differentiation and unbalanced autophagy in type 2 Familial Partial Lipodystrophy: an in vitro and in vivo study of adipose tissue browning. Journal Article

Experimental & molecular medicine., 51 (8), pp. 89, 2019.

Abstract | Links | BibTeX

Cenni V; Kojic S; Capanni C; Faulkner G; Lattanzi G

Ankrd2 in Mechanotransduction and Oxidative Stress Response in Skeletal Muscle: New Cues for the Pathogenesis of Muscular Laminopathies. Journal Article

Oxidative medicine and cellular longevity, 2019 , pp. 7318796, 2019, (Review).

Abstract | Links | BibTeX

Mattioli E; Andrenacci D; Mai A; Valente S; Robijns J; De Vos WH; Capanni C; Lattanzi G

Statins and Histone Deacetylase Inhibitors Affect Lamin A/C - Histone Deacetylase 2 Interaction in Human Cells. Journal Article

Frontiers in cell and developmental biology, 7 , pp. 6, 2019.

Abstract | Links | BibTeX

2017

Angori S; Capanni C; Faulkner G; Bean C; Boriani G; Lattanzi G; Cenni V

Emery-Dreifuss Muscular Dystrophy-Associated Mutant Forms of Lamin A Recruit the Stress Responsive Protein Ankrd2 into the Nucleus, Affecting the Cellular Response to Oxidative Stress. Journal Article

Cellular Physiology and Biochemistry, 42 , pp. 169-184, 2017.

Abstract | Links | BibTeX

2016

Loi M; Cenni V; Duchi S; Squarzoni S; Lopez-Otin C; Foisner R; Lattanzi G; Capanni C

Barrier-to-Autointegration Factor (BAF) involvement in prelamin A-related chromatin organization changes. Journal Article

Oncotarget, 7 (13), pp. 15662-15677, 2016.

Abstract | Links | BibTeX

Bellotti C; Capanni C; Lattanzi G; Donati D; Lucarelli E; Duchi S

Detection of mesenchymal stem cells senescence by prelamin A accumulation at the nuclear level. Journal Article

Springerplus, 5 (1), pp. 1427, 2016.

Abstract | Links | BibTeX

2015

Pellegrini C; Columbaro M; Capanni C; D'Apice MR; Cavallo C; Murdocca M; Lattanzi G; Squarzoni S

All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype. Journal Article

Oncotarget, 6 (30), pp. 29914-29928, 2015.

Abstract | Links | BibTeX

Ravera S; Capanni C; Tognotti D; Bottega R; Columbaro M; Dufour C; Cappelli E; Degan P

Inhibition of metalloproteinase activity in FANCA is linked to altered oxygen metabolism. Journal Article

Journal of Cellular Physiology, 230 (3), 2015.

Abstract | Links | BibTeX

Piva R; Lambertini E; Manferdini C; Capanni C; Penolazzi L; Gabusi E; Paolella F; Lolli A; Angelozzi M; Lattanzi G; Lisignoli G

Slug transcription factor and nuclear Lamin B1 are upregulated in osteoarthritic chondrocytes. Journal Article

Osteoarthritis and Cartilage, 23 (7), pp. 1226-1230, 2015.

Abstract | Links | BibTeX

2014

Camozzi D; Capanni C; Cenni V; Mattioli E; Columbaro M; Squarzoni S; Lattanzi G

Diverse lamin-dependent mechanisms interact to control chromatin dynamics: Focus on laminopathies Journal Article

Nucleus, 5 , pp. 427-440, 2014, ISSN: 1949-1034.

Abstract | Links | BibTeX

Lattanzi G; Ortolani M; Columbaro M; Prencipe S; Mattioli E; Lanzarini C; Maraldi NM; Cenni V; Garagnani P; Salvioli S; Storci G; Bonafe' M; Capanni C; Franceschi C

Lamins are rapamycin targets that impact human longevity: A study in centenarians Journal Article

Journal of Cell Science, 127 , pp. 147-157, 2014, ISSN: 1477-9137.

Abstract | Links | BibTeX

Capanni C; Mattioli E; Columbaro M; Wehnert M; Ortolani M; Fini M; Novelli G; Bertacchini J; Maraldi NM; Marmiroli S; D'Apice MR; Prencipe S; Squarzoni S; Lattanzi G; Cenni V

Rapamycin treatment of Mandibuloacral Dysplasia cells rescues localization of chromatin-associated proteins and cell cycle dynamics Journal Article

Aging (Albany, N.Y. Online), 6 , pp. 755–770, 2014, ISSN: 1945-4589.

Abstract | Links | BibTeX

Ravera S; Capanni C; Panfoli I; Cuccarolo P; Stroppiana G; Degan P; Cappelli E; Columbaro M

Treatment of FANCA Cells with Resveratrol and N-Acetylcysteine: A Comparative Study Journal Article

PloS one, 9 , pp. e104857, 2014, ISSN: 1932-6203.

Abstract | Links | BibTeX