Camilla Evangelisti


Istituto di Genetica Molecolare “Luigi Luca Cavalli-Sforza” – Sede di Bologna
c/o Istituto Ortopedico Rizzoli -via di Barbiano 1/10
40136 Bologna 
Phone: +39 051 2091581

E-mail: camilla.evangelisti@area.cnr.bo.it

Curriculum Vitae – Download

Elenco completo delle pubblicazioni – Download

Attività di ricerca

  • Fenomeni di TRASDUZIONE DEL SEGNALE basati sui polifosfoinositidi e sulla protein chinasi C a livello nucleare durante la proliferazione ed il differenziamento cellulare.
  • Analisi della TRASDUZIONE DEL SEGNALE di isoforme della diacilglicerolo chinasi a livello nucleare in seguito a stimoli proliferativi e differenziativi in cellule mioblastiche.
  • Vie di TRASDUZIONE DEL SEGNALE imperniate su fosfoinositide 3-chinasi/Akt/mTOR e Raf/MEK/Erk nella farmacoresistenza di cellule leucemiche umane e murine.
  • Coinvolgimento di vie di TRASDUZIONE DEL SEGNALE (TGFbeta, PI3K/Akt/mTOR e Raf/MEK/Erk) in laminopatie.
  • Fenomeni di TRASDUZIONE DEL SEGNALE e MECCANOSIGNALING nello studio dell’unità muscolo-tendinea e malattie associate come la distrofia muscolare e le tendinopatie legate all’età
  • Studio delle lamine nei tumori ossei

Gruppo di ricerca

Francesca Chiarini

Elisabetta Mattioli

Vittoria Cenni

Patrizia Sabatelli

Giovanna Lattanzi

 


Pubblicazioni Recenti

2021

Martelli AM; Evangelisti C; Paganelli F; Chiarini F; McCubrey JA

GSK-3: a multifaceted player in acute leukemias Journal Article Forthcoming

In: Leukemia, Forthcoming.

Abstract | Links | BibTeX

2020

Ratti S; Lonetti A; Follo MY; Paganelli F; Martelli AM; Chiarini F; Evangelisti C

B-ALL Complexity: Is Targeted Therapy Still A Valuable Approach for Pediatric Patients? Journal Article

In: Cancers, 12 (12), pp. E3498, 2020.

Abstract | Links | BibTeX

Evangelisti C; Chiarini F; Paganelli F; Marmiroli S; Martelli AM

Crosstalks of GSK3 signaling with the mTOR network and effects on targeted therapy of cancer. Journal Article

In: Biochimica et biophysica acta. Molecular cell research, 1867 (4), pp. 118635, 2020.

Abstract | Links | BibTeX

Evangelisti C; Paganelli F; Giuntini G; Mattioli E; Cappellini A; Ramazzotti G; Faenza I; Maltarello MC; Martelli AM; Scotlandi K; Chiarini F; Lattanzi G

Lamin A and Prelamin A Counteract Migration of Osteosarcoma Cells Journal Article

In: Cells, 9 (3), pp. 774, 2020.

Abstract | Links | BibTeX

Evangelisti C; Chiarini F; Cappellini A; Paganelli F; Fini M; Santi S; Martelli AM; Neri LM; Evangelisti C

Targeting Wnt/beta-catenin and PI3K/Akt/mTOR pathways in T-cell acute lymphoblastic leukemia. Journal Article

In: Journal of cellular physiology, 235 (6), pp. 5413-5428, 2020.

Abstract | Links | BibTeX

Chiarini F; Paganelli F; Martelli AM; Evangelisti C

The Role Played by Wnt/beta-Catenin Signaling Pathway in Acute Lymphoblastic Leukemia. Journal Article

In: International journal of molecular sciences, 21 (3), pp. e1098, 2020.

Abstract | Links | BibTeX

Martelli AM; Paganelli F; Chiarini F; Evangelisti C; McCubrey JA

The Unfolded Protein Response: A Novel Therapeutic Target in Acute Leukemias. Journal Article

In: Cancers, 12 (2), pp. e333, 2020.

Abstract | Links | BibTeX

2019

Chiarini F; Evangelisti C; Lattanzi G; McCubrey JA; Martelli AM

Advances in understanding the mechanisms of evasive and innate resistance to mTOR inhibition in cancer cells. Journal Article

In: Biochimica et biophysica acta. Molecular cell research, 1866 (8), pp. 1322-1337, 2019.

Abstract | Links | BibTeX

Evangelisti C; Chiarini F; Paganelli F; Marmiroli S; Martelli AM

Crosstalks of GSK3 signaling with the mTOR network and effects on targeted therapy of cancer. Journal Article

In: Biochimica et biophysica acta. Molecular cell research, 1867 (4), pp. 118635, 2019.

Abstract | Links | BibTeX

Paganelli F; Lonetti A; Anselmi L; Martelli AM; Evangelisti C; Chiarini F

New advances in targeting aberrant signaling pathways in T-cell acute lymphoblastic leukemia. Journal Article

In: Advances in biological regulation, 74 , pp. 100649, 2019.

Abstract | Links | BibTeX

Chiarini F; Evangelisti C; Cenni V; Fazio A; Paganelli F; Martelli AM; Lattanzi G

The Cutting Edge: The Role of mTOR Signaling in Laminopathies. Journal Article

In: International journal of molecular sciences, 20 (4), pp. E847, 2019.

Abstract | Links | BibTeX

2018

Bernasconi P; Carboni N; Ricci G; Siciliano G; Politano L; Maggi L; Mongini T; Vercelli L; Rodolico C; Biagini E; Boriani G; Ruggiero L; Santoro L; Schena E; Prencipe S; Evangelisti C; Pegoraro E; Morandi L; Columbaro M; Lanzuolo C; Sabatelli P; Cavalcante P; Cappelletti C; Bonne G; Muchir A; Lattanzi G

Elevated TGF beta2 serum levels in Emery-Dreifuss muscular dystrophy: implications for myocyte and tenocyte differentiation and fibrogenic processes. Journal Article

In: Nucleus, 25 (1), pp. 24, 2018.

Abstract | Links | BibTeX

Evangelisti C; Cappellini A; Oliveira M; Fragoso R; Barata JT; Bertaina A; Locatelli F; Simioni C; Neri LM; Chiarini F; Lonetti A; Buontempo F; Orsini E; Pession A; Manzoli L; Martelli AM; Evangelisti C

Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia. Journal Article

In: Journal of cellular physiology, 233 (3), pp. 1796-1811, 2018.

Abstract | Links | BibTeX

Buontempo F; McCubrey JA; Orsini E; Ruzzene M; Cappellini A; Lonetti A; Evangelisti C; Chiarini F; Evangelisti C; Barata JT; Martelli AM

Therapeutic targeting of CK2 in acute and chronic leukemias. Journal Article

In: Leukemia, 32 (1), pp. 1-10, 2018.

Abstract | Links | BibTeX

Evangelisti C; Chiarini F; McCubrey JA; Martelli AM

Therapeutic Targeting of mTOR in T-Cell Acute Lymphoblastic Leukemia: An Update. Journal Article

In: International journal of molecular sciences, 19 (7), pp. pii: E1878, 2018.

Abstract | Links | BibTeX

2017

Ultimo S; Simioni C; Martelli AM; Zauli G; Evangelisti C; Celeghini C; McCubrey JA; Marisi G; Ulivi P; Capitani S; Neri LM

PI3K isoform inhibition associated with anti Bcr-Abl drugs shows in vitro increased anti-leukemic activity in Philadelphia chromosome-positive B-acute lymphoblastic leukemia cell lines. Journal Article

In: Oncotarget, 8 (14), pp. 23213-23227, 2017.

Abstract | Links | BibTeX

2016

Chiarini F; Lonetti A; Evangelisti C; Buontempo F; Orsini E; Evangelisti C; Cappellini A; Neri LM; McCubrey JA; Martelli AM

Advances in understanding the acute lymphoblastic leukemia bone marrow microenvironment: From biology to therapeutic targeting. Journal Article

In: Biochimica Et Biophysica Acta (BBA) - Molecular Cell Research, 1863 (3), pp. 449-463, 2016.

Abstract | Links | BibTeX

Lonetti A; Cappellini A; Bertaina A; Locatelli F; Pession A; Buontempo F; Evangelisti C; Evangelisti C; Orsini E; Zambonin L; Neri LM; Martelli AM; Chiarini F

Improving nelarabine efficacy in T cell acute lymphoblastic leukemia by targeting aberrant PI3K/AKT/mTOR signaling pathway. Journal Article

In: Journal Of Hematology & Oncology , 9 (1), pp. 114, 2016.

Abstract | Links | BibTeX

Evangelisti C; Cenni V; Lattanzi G

Potential therapeutic effects of the mtor inhibitors for preventing ageing and progeria-related disorders. Journal Article

In: British Journal of Clinical Pharmacology (Literature Review), 82 (5), pp. 1229-1244, 2016.

Abstract | Links | BibTeX

Buontempo F; Orsini E; Lonetti A; Cappellini A; Chiarini F; Evangelisti C; Evangelisti C; Melchionda F; Pession A; Bertaina A; Locatelli F; Bertacchini J; Neri LM; McCubrey JA; Martelli AM

Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-κB. Journal Article

In: Oncotarget, 7 (2), pp. 1323-1340, 2016.

Abstract | Links | BibTeX

Evangelisti C; Evangelisti C; Buontempo F; Lonetti A; Orsini E; Chiarini F; Barata JT; Pyne S; Pyne NJ; Martelli AM

Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies. Journal Article

In: Leukemia, 30 (11), pp. 2142-2151, 2016.

Abstract | Links | BibTeX

2015

Evangelisti C; Evangelisti C; Chiarini F; Lonetti A; Buontempo F; Neri LM; McCubrey JA; Martelli AM

Autophagy in acute leukemias: A double-edged sword with important therapeutic implications Journal Article

In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1853 (1), pp. 14-26, 2015.

Abstract | Links | BibTeX

Chiarini F; Evangelisti C; McCubrey JA; Martelli AM

Current treatment strategies for inhibiting mTOR in cancer Journal Article

In: Trends in Pharmacological Sciences, 36 (2), 2015.

Abstract | Links | BibTeX

Evangelisti C; Bernasconi P; Cavalcante P; Cappelletti C; D'Apice MR; Sbraccia P; Novelli G; Prencipe S; Lemma S; Baldini N; Avnet S; Squarzoni S; Martelli AM; Lattanzi G

Modulation of TGFbeta 2 levels by lamin A in U2-OS osteoblast-like cells: understanding the osteolytic process triggered by altered lamins. Journal Article

In: Oncotarget, 6 (10), pp. 7424-7437, 2015.

Abstract | Links | BibTeX

Lonetti A; Cappellini A; Spartà AM; Chiarini F; Buontempo F; Evangelisti C; Evangelisti C; Orsini E; McCubrey JA; Martelli AM

PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors. Journal Article

In: Oncotarget, 6 (12), pp. 10399-10414, 2015.

Abstract | Links | BibTeX