Camilla Evangelisti


Istituto di Genetica Molecolare “Luigi Luca Cavalli-Sforza” – Sede di Bologna
c/o Istituto Ortopedico Rizzoli -via di Barbiano 1/10
40136 Bologna 
Phone: +39 051 2091581

E-mail: camilla.evangelisti@area.cnr.bo.it

Curriculum Vitae – Download

Complete List of Publications – Download

 

Research Activity

    • Study of involvement of nuclear Protein Kinase C and poliphosphoinosidites in proliferation and differentiation
    • Study of laminopathies and lamin-associated signaling pathways in aging and disease
    • Study of mechanosignaling in muscle-tendon (MTU) unit models and diseases associated as muscular dystrophies (MDs) and aging-related tendinopathies
    • Study of involvement of PI3K/Akt/mTOR pathway in proliferation, survival and drug resistance of human leukemia cells. This pathway could represent a target for innovative therapeutic strategies for treating leukemia patients
    • Study of DGK lipid-dependent signal transduction pathways in myogenic cells
    • Study of Lamins in bone sarcomas

Research Project

Research Group

Francesca Chiarini

Elisabetta Mattioli

Vittoria Cenni

Patrizia Sabatelli

Giovanna Lattanzi

Recent Publications

2024

Cenni V; Evangelisti C; Santi S; Sabatelli P; Neri S; Cavallo M; Lattanzi G; Mattioli E

Desmin and Plectin Recruitment to the Nucleus and Nuclei Orientation Are Lost in Emery-Dreifuss Muscular Dystrophy Myoblasts Subjected to Mechanical Stimulation Journal Article

In: Cells, vol. 13, iss. 2, pp. 162, 2024.

Abstract | Links | BibTeX

2022

Chiarini F; Paganelli F; Balestra T; Capanni C; Fazio A; Manara MC; Landuzzi L; Petrini S; Evangelisti C; Lollini PL; Martelli AM; Lattanzi G; Scotlandi K

Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma Journal Article

In: Cell death & disease, vol. 13, iss. 4, pp. 346, 2022.

Abstract | Links | BibTeX

Evangelisti C; Rusciano I; Mongiorgi S; Ramazzotti G; Lattanzi G; Manzoli L; Cocco L; Ratti S and

The wide and growing range of lamin B-related diseases: from laminopathies to cancer. Journal Article

In: Cellular and molecular life sciences, vol. 79, iss. 2, no. 126, 2022.

Abstract | Links | BibTeX

2021

Martelli AM; Evangelisti C; Paganelli F; Chiarini F; McCubrey JA

GSK-3: a multifaceted player in acute leukemias Journal Article

In: Leukemia, vol. 35, iss. 7, no. 1829, pp. 1842, 2021.

Abstract | Links | BibTeX

2020

Ratti S; Lonetti A; Follo MY; Paganelli F; Martelli AM; Chiarini F; Evangelisti C

B-ALL Complexity: Is Targeted Therapy Still A Valuable Approach for Pediatric Patients? Journal Article

In: Cancers, vol. 12, no. 12, pp. E3498, 2020.

Abstract | Links | BibTeX

Evangelisti C; Chiarini F; Paganelli F; Marmiroli S; Martelli AM

Crosstalks of GSK3 signaling with the mTOR network and effects on targeted therapy of cancer. Journal Article

In: Biochimica et biophysica acta. Molecular cell research, vol. 1867, no. 4, pp. 118635, 2020.

Abstract | Links | BibTeX

Evangelisti C; Paganelli F; Giuntini G; Mattioli E; Cappellini A; Ramazzotti G; Faenza I; Maltarello MC; Martelli AM; Scotlandi K; Chiarini F; Lattanzi G

Lamin A and Prelamin A Counteract Migration of Osteosarcoma Cells Journal Article

In: Cells, vol. 9, no. 3, pp. 774, 2020.

Abstract | Links | BibTeX

Evangelisti C; Chiarini F; Cappellini A; Paganelli F; Fini M; Santi S; Martelli AM; Neri LM; Evangelisti C

Targeting Wnt/beta-catenin and PI3K/Akt/mTOR pathways in T-cell acute lymphoblastic leukemia. Journal Article

In: Journal of cellular physiology, vol. 235, no. 6, pp. 5413-5428, 2020.

Abstract | Links | BibTeX

Chiarini F; Paganelli F; Martelli AM; Evangelisti C

The Role Played by Wnt/beta-Catenin Signaling Pathway in Acute Lymphoblastic Leukemia. Journal Article

In: International journal of molecular sciences, vol. 21, no. 3, pp. e1098, 2020.

Abstract | Links | BibTeX

Martelli AM; Paganelli F; Chiarini F; Evangelisti C; McCubrey JA

The Unfolded Protein Response: A Novel Therapeutic Target in Acute Leukemias. Journal Article

In: Cancers, vol. 12, no. 2, pp. e333, 2020.

Abstract | Links | BibTeX

2019

Chiarini F; Evangelisti C; Lattanzi G; McCubrey JA; Martelli AM

Advances in understanding the mechanisms of evasive and innate resistance to mTOR inhibition in cancer cells. Journal Article

In: Biochimica et biophysica acta. Molecular cell research, vol. 1866, no. 8, pp. 1322-1337, 2019.

Abstract | Links | BibTeX

Evangelisti C; Chiarini F; Paganelli F; Marmiroli S; Martelli AM

Crosstalks of GSK3 signaling with the mTOR network and effects on targeted therapy of cancer. Journal Article

In: Biochimica et biophysica acta. Molecular cell research, vol. 1867, no. 4, pp. 118635, 2019.

Abstract | Links | BibTeX

Paganelli F; Lonetti A; Anselmi L; Martelli AM; Evangelisti C; Chiarini F

New advances in targeting aberrant signaling pathways in T-cell acute lymphoblastic leukemia. Journal Article

In: Advances in biological regulation, vol. 74, pp. 100649, 2019.

Abstract | Links | BibTeX

Chiarini F; Evangelisti C; Cenni V; Fazio A; Paganelli F; Martelli AM; Lattanzi G

The Cutting Edge: The Role of mTOR Signaling in Laminopathies. Journal Article

In: International journal of molecular sciences, vol. 20, no. 4, pp. E847, 2019.

Abstract | Links | BibTeX

2018

Bernasconi P; Carboni N; Ricci G; Siciliano G; Politano L; Maggi L; Mongini T; Vercelli L; Rodolico C; Biagini E; Boriani G; Ruggiero L; Santoro L; Schena E; Prencipe S; Evangelisti C; Pegoraro E; Morandi L; Columbaro M; Lanzuolo C; Sabatelli P; Cavalcante P; Cappelletti C; Bonne G; Muchir A; Lattanzi G

Elevated TGF beta2 serum levels in Emery-Dreifuss muscular dystrophy: implications for myocyte and tenocyte differentiation and fibrogenic processes. Journal Article

In: Nucleus, vol. 25, no. 1, pp. 24, 2018.

Abstract | Links | BibTeX

Evangelisti C; Cappellini A; Oliveira M; Fragoso R; Barata JT; Bertaina A; Locatelli F; Simioni C; Neri LM; Chiarini F; Lonetti A; Buontempo F; Orsini E; Pession A; Manzoli L; Martelli AM; Evangelisti C

Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia. Journal Article

In: Journal of cellular physiology, vol. 233, no. 3, pp. 1796-1811, 2018.

Abstract | Links | BibTeX

Buontempo F; McCubrey JA; Orsini E; Ruzzene M; Cappellini A; Lonetti A; Evangelisti C; Chiarini F; Evangelisti C; Barata JT; Martelli AM

Therapeutic targeting of CK2 in acute and chronic leukemias. Journal Article

In: Leukemia, vol. 32, no. 1, pp. 1-10, 2018.

Abstract | Links | BibTeX

Evangelisti C; Chiarini F; McCubrey JA; Martelli AM

Therapeutic Targeting of mTOR in T-Cell Acute Lymphoblastic Leukemia: An Update. Journal Article

In: International journal of molecular sciences, vol. 19, no. 7, pp. pii: E1878, 2018.

Abstract | Links | BibTeX

2017

Ultimo S; Simioni C; Martelli AM; Zauli G; Evangelisti C; Celeghini C; McCubrey JA; Marisi G; Ulivi P; Capitani S; Neri LM

PI3K isoform inhibition associated with anti Bcr-Abl drugs shows in vitro increased anti-leukemic activity in Philadelphia chromosome-positive B-acute lymphoblastic leukemia cell lines. Journal Article

In: Oncotarget, vol. 8, no. 14, pp. 23213-23227, 2017.

Abstract | Links | BibTeX

2016

Chiarini F; Lonetti A; Evangelisti C; Buontempo F; Orsini E; Evangelisti C; Cappellini A; Neri LM; McCubrey JA; Martelli AM

Advances in understanding the acute lymphoblastic leukemia bone marrow microenvironment: From biology to therapeutic targeting. Journal Article

In: Biochimica Et Biophysica Acta (BBA) - Molecular Cell Research, vol. 1863, no. 3, pp. 449-463, 2016.

Abstract | Links | BibTeX

Lonetti A; Cappellini A; Bertaina A; Locatelli F; Pession A; Buontempo F; Evangelisti C; Evangelisti C; Orsini E; Zambonin L; Neri LM; Martelli AM; Chiarini F

Improving nelarabine efficacy in T cell acute lymphoblastic leukemia by targeting aberrant PI3K/AKT/mTOR signaling pathway. Journal Article

In: Journal Of Hematology & Oncology , vol. 9, no. 1, pp. 114, 2016.

Abstract | Links | BibTeX

Evangelisti C; Cenni V; Lattanzi G

Potential therapeutic effects of the mtor inhibitors for preventing ageing and progeria-related disorders. Journal Article

In: British Journal of Clinical Pharmacology (Literature Review), vol. 82, no. 5, pp. 1229-1244, 2016.

Abstract | Links | BibTeX

Buontempo F; Orsini E; Lonetti A; Cappellini A; Chiarini F; Evangelisti C; Evangelisti C; Melchionda F; Pession A; Bertaina A; Locatelli F; Bertacchini J; Neri LM; McCubrey JA; Martelli AM

Synergistic cytotoxic effects of bortezomib and CK2 inhibitor CX-4945 in acute lymphoblastic leukemia: turning off the prosurvival ER chaperone BIP/Grp78 and turning on the pro-apoptotic NF-κB. Journal Article

In: Oncotarget, vol. 7, no. 2, pp. 1323-1340, 2016.

Abstract | Links | BibTeX

Evangelisti C; Evangelisti C; Buontempo F; Lonetti A; Orsini E; Chiarini F; Barata JT; Pyne S; Pyne NJ; Martelli AM

Therapeutic potential of targeting sphingosine kinases and sphingosine 1-phosphate in hematological malignancies. Journal Article

In: Leukemia, vol. 30, no. 11, pp. 2142-2151, 2016.

Abstract | Links | BibTeX

2015

Evangelisti C; Evangelisti C; Chiarini F; Lonetti A; Buontempo F; Neri LM; McCubrey JA; Martelli AM

Autophagy in acute leukemias: A double-edged sword with important therapeutic implications Journal Article

In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol. 1853, no. 1, pp. 14-26, 2015.

Abstract | Links | BibTeX

Chiarini F; Evangelisti C; McCubrey JA; Martelli AM

Current treatment strategies for inhibiting mTOR in cancer Journal Article

In: Trends in Pharmacological Sciences, vol. 36, no. 2, 2015.

Abstract | Links | BibTeX

Evangelisti C; Bernasconi P; Cavalcante P; Cappelletti C; D'Apice MR; Sbraccia P; Novelli G; Prencipe S; Lemma S; Baldini N; Avnet S; Squarzoni S; Martelli AM; Lattanzi G

Modulation of TGFbeta 2 levels by lamin A in U2-OS osteoblast-like cells: understanding the osteolytic process triggered by altered lamins. Journal Article

In: Oncotarget, vol. 6, no. 10, pp. 7424-7437, 2015.

Abstract | Links | BibTeX

Lonetti A; Cappellini A; Spartà AM; Chiarini F; Buontempo F; Evangelisti C; Evangelisti C; Orsini E; McCubrey JA; Martelli AM

PI3K pan-inhibition impairs more efficiently proliferation and survival of T-cell acute lymphoblastic leukemia cell lines when compared to isoform-selective PI3K inhibitors. Journal Article

In: Oncotarget, vol. 6, no. 12, pp. 10399-10414, 2015.

Abstract | Links | BibTeX