IGM PUBLICATIONS

598 entries « 1 of 15 »

Giordani G; Cavaliere V; Gargiulo G; Lattanzi G; Andrenacci D

Retrotransposons Down- and Up-Regulation in Aging Somatic Tissue Journal Article

In: Cells, 11 (1), pp. 79, 2021.

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Zardoni L; Nardini E; Brambati A; Lucca C; Choudhary R; Loperfido F; Sabbioneda S; Liberi G

Elongating RNA polymerase II and RNA:DNA hybrids hinder fork progression and gene expression at sites of head-on replication-transcription collisions Journal Article

In: Nucleic acids research, 49 (22), pp. 12769-12784, 2021.

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Pelizzo G; Riva F; Croce S; Avanzini MA; Acquafredda G; de Silvestri A; Mazzon E; Bramanti P; Zuccotti G; Mazzini G; Calcaterra V

Proliferation Pattern of Pediatric Tumor-Derived Mesenchymal Stromal Cells and Role in Cancer Dormancy: A Perspective of Study for Surgical Strategy Journal Article

In: Frontiers in pediatrics, 9 , pp. 766610, 2021.

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Pavani M; Bonaiuti P; Chiroli E; Gross F; Natali F; Macaluso F; Poti A; Pasqualato S; Farkas Z; Pompei S; Cosentino Lagomarsino M; Rancati G; Szüts D; Ciliberto A

Epistasis, aneuploidy, and functional mutations underlie evolution of resistance to induced microtubule depolymerization Journal Article

In: EMBO Journal, 40 (22), pp. e108225, 2021.

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Paganelli F; Chiarini F; Palmieri A; Martinelli M; Sena P; Bertacchini J; Roncucci L; Cappellini A; Martelli AM; Bonucci M; Fiorentini C; Hammarberg Ferri I

The Combination of AHCC and ETAS Decreases Migration of Colorectal Cancer Cells, and Reduces the Expression of LGR5 and Notch1 Genes in Cancer Stem Cells: A Novel Potential Approach for Integrative Medicine Journal Article

In: Pharmaceuticals, 14 (12), pp. 1325, 2021.

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Napoletano F; Ferrari Bravo G; Voto IAP; Santin A; Celora L; Campaner E; Dezi C; Bertossi A; Valentino E; Santorsola M; Rustighi A; Fajner V; Maspero E; Ansaloni F; Cancila V; Valenti CF; Santo M; Artimagnella OB; Finaurini S; Gioia U; Polo S; Sanges R; Tripodo C; Mallamaci A; Gustincich S; d'Adda di Fagagna F; Mantovani F; Specchia V; Del Sal G

The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress Journal Article

In: Cell reports, 36 (11), pp. 109694, 2021.

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Humphreys IR; Pei J; Baek M; Krishnakumar A; Anishchenko I; Ovchinnikov S; Zhang J; Ness TJ; Banjade S; Bagde SR; Stancheva VG; Li XH; Liu K; Zheng Z; Barrero DJ; Roy U; Kuper J; Fernández IS; Szakal B; Branzei D; Rizo J; Kisker C; Greene EC; Biggins S; Keeney S; Miller EA; Fromme JC; Hendrickson TL; Cong Q; Baker D

Computed structures of core eukaryotic protein complexes. Journal Article

In: Science, 374 (6573), 2021.

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Graham SE; Clarke SL; Wu KH; Kanoni S; Zajac GJM ......; Biino G; et al.

The power of genetic diversity in genome-wide association studies of lipids. Journal Article

In: Nature, 600 (7890), pp. 675-679, 2021.

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Bacalini MG; Palombo F; Garagnani P; Giuliani C; Fiorini C; Caporali L; Stanzani Maserati M; Capellari S; Romagnoli M; De Fanti S; Benussi L; Binetti G; Ghidoni R; Galimberti D; Scarpini E; Arcaro M; Bonanni E; Siciliano G; Maestri M; Guarnieri B; Italian Multicentric Group on clock genes; actigraphy in AD; Martucci M; Monti D; Carelli V; Franceschi C; La Morgia C; Santoro A.

Association of rs3027178 polymorphism in the circadian clock gene PER1 with susceptibility to Alzheimer's disease and longevity in an Italian population Journal Article Forthcoming

In: Geroscience, Forthcoming.

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Sepe S; Rossiello F; Cancila V; Iannelli F; Matti V; Cicio G; Cabrini M; Marinelli E; Alabi BR; di Lillo A; Di Napoli A; Shay JW; Tripodo C; d'Adda di Fagagna F

DNA damage response at telomeres boosts the transcription of SARS-CoV-2 receptor ACE2 during aging. Journal Article Forthcoming

In: EMBO Reports, Forthcoming.

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Piazzi M; Bavelloni A; Cenni V; Faenza I; Blalock WL

Revisiting the Role of GSK3, A Modulator of Innate Immunity, in Idiopathic Inclusion Body Myositis. Journal Article

In: Cells, 10 (11), pp. 3255, 2021.

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Brai A; Riva V; Clementi L; Falsitta L; Zamperini C; Sinigiani V; Festuccia C; Sabetta S; Aiello D; Roselli C; Garbelli A; Trivisani CI; Maccari L; Bugli F; Sanguinetti M; Calandro P; Chiariello M; Quaranta P; Botta L; Angelucci A; Maga G; Botta M

Targeting DDX3X Helicase Activity with BA103 Shows Promising Therapeutic Effects in Preclinical Glioblastoma Models Journal Article

In: Cancers (Basel), 13 (21), pp. 5569, 2021.

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Avnet S; Lemma S; Cortini M; Di Pompo G; Perut F; Lipreri MV; Roncuzzi L; Columbaro M; Errani C; Longhi A; Zini N; Heymann D; Dominici M; Grisendi G; Golinelli G; Consolino L; Longo DL; Nanni C; Righi A; Baldini N

Release of Inflammatory Mediators from Acid-Stimulated Mesenchymal Stromal Cells Favours Tumour Invasiveness and Metastasis in Osteosarcoma. Journal Article

In: Cancers (Basel), 13 (22), pp. 5855, 2021.

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Falzarano MS; Rossi R; Grilli A; Fang M; Osman H; Sabatelli P; Antoniel M; Lu Z; Li W; Selvatici R; Al-Khalili C; Gualandi F; Bicciato S; Torelli S; Ferlini A

Urine-Derived Stem Cells Express 571 Neuromuscular Disorders Causing Genes, Making Them a Potential in vitro Model for Rare Genetic Diseases. Journal Article

In: Frontiers in physiology, 12 , pp. 716471, 2021.

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Scolari F; Khamis FM; Perez-Staples D

Beyond Sperm and Male Accessory Gland Proteins: Exploring Insect Reproductive Metabolomes Journal Article

In: Frontiers in physiology, 12 (1), pp. Frontiers in physiology, 2021.

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Pirota V; Lunghi E; Benassi A; Crespan E; Freccero M; Doria F

Selective Binding and Redox-Activity on Parallel G-Quadruplexes by Pegylated Naphthalene Diimide-Copper Complexes Journal Article

In: Molecules, 26 (16), pp. 5025, 2021.

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Olivotto E; Minguzzi M; D'Adamo S; Astolfi A; Santi S; Uguccioni M; Marcu KB; Borzi' RM

Basal and IL-1beta enhanced chondrocyte chemotactic activity on monocytes are co-dependent on both IKKalpha and IKKbeta NF-kappaB activating kinases Journal Article

In: Scientific reports, 11 (1), pp. 21697, 2021.

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Kawasumi R; Abe T; Psakhye I; Miyata K; Hirota K; Branzei D

Vertebrate CTF18 and DDX11 essential function in cohesion is bypassed by preventing WAPL-mediated cohesin release Journal Article

In: Genes & development, 35 (19-20), pp. 1368-1382, 2021.

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Grazia Martina M; Vicenti I; Bauer L; Crespan E; Rango E; Boccuto A; Olivieri N; Incerti M; Zwaagstra M; Allodi M; Bertoni S; Dreassi E; Zazzi M; van Kuppeveld FJM; Maga G; Radi M

Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIBETA) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses Journal Article Forthcoming

In: ChemMedChem, Forthcoming.

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Vignoli B; Sansevero G; Sasi M; Rimondini R; Blum R; Bonaldo V; Biasini E; Santi S; Berardi N; Lu B; Canossa M

Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention Journal Article

In: Communications biology, 4 (1), pp. 1152, 2021.

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Savini G; Scolari F; Ometto L; Rota-Stabelli O; Carraretto D; Gomulski LM; Gasperi G; Abd-Alla AMM; Aksoy S; Attardo GM; Malacrida AR

Viviparity and habitat restrictions may influence the evolution of male reproductive genes in tsetse fly (Glossina) species Journal Article

In: BMC biology, 19 (1), 2021.

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Lanzafame M; Branca G; Landi C; Qiang M; Vaz B; Nardo T; Ferri D; Mura M; Iben S; Stefanini M; Peverali FA; Bini L; Orioli D

Cockayne syndrome group A and ferrochelatase finely tune ribosomal gene transcription and its response to UV irradiation Journal Article Forthcoming

In: Nucleic Acids Research, Forthcoming.

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Choi N; Liu Y; Oh J; Ha J; Ghigna C; Zheng X; Shen H

Relative strength of 5' splice-site strength defines functions of SRSF2 and SRSF6 in alternative splicing of Bcl-x pre-mRNA Journal Article

In: BMC Reports, 54 (3), pp. 176-181, 2021.

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Chiavaroli A; Balaha M; Acquaviva A; Ferrante C; Cataldi A; Menghini L; Rapino M; Orlando G; Brunetti L; Leone S; Recinella L; di Giacomo V

Phenolic Characterization and Neuroprotective Properties of Grape Pomace Extracts Journal Article

In: Molecules, 26 (20), pp. 6216, 2021.

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Carano F; Teti G; Ruggeri A; Chiarini F; Giorgetti A; Mazzotti MC; Fais P; Falconi M

Assessment of the structural and functional characteristics of human mesenchymal stem cells associated with a prolonged exposure of morphine Journal Article

In: Scientific Reports, 11 (1), pp. 19248, 2021.

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Salviato E; Djordjilovic V; Hariprakash JM; Tagliaferri I; Pal K; Ferrari F

Leveraging three-dimensional chromatin architecture for effective reconstruction of enhancer-target gene regulatory interactions Journal Article

In: Nucleic acids research, 49 (17), 2021.

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Tideman JWL; Parssinen O; Haarman AEG; Khawaja AP; Wedenoja J; Williams KM; Biino G; Ding X; Kahonen M; Lehtimaki T; Raitakari OT; Cheng CY; Jonas JB; Young TL; Bailey-Wilson JE; Rahi J; Williams C; He M; Mackey DA; Guggenheim JA; UK Biobank Eye; Vision Consortium; the Consortium for Refractive Error; Myopia (CREAM Consortium)

Evaluation of Shared Genetic Susceptibility to High and Low Myopia and Hyperopia Journal Article

In: JAMA ophthalmology, 139 (6), pp. 601-609, 2021.

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Van Beek JJP; Puccio S; Roberto A; De Paoli F; Graziano G; Salviato E; Alvisi G; Zanon V; Scarpa A; Zaghi E; Calvi M; Di Vito C; Mineri R; Sarina B; De Philippis C; Santoro A; Mariotti J; Bramanti S; Ferrari F; Castagna L; Mavilio D; Lugli E

Single-cell profiling reveals the dynamics of cytomegalovirusspecific T-cells in haploidentical hematopoietic stem cell transplantation Journal Article

In: Haematologica, 106 (10), pp. 2768-2773, 2021.

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Scaglia N; Frontini-Lopez YR; Zadra G

Prostate Cancer Progression: as a Matter of Fats Natalia Journal Article

In: Frontiers in oncology, 11 , pp. 719865, 2021.

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Pellegrini C; Pirazzini C; Sala C; Sambati L; Yusipov I; Kalyakulina A; Ravaioli F; Kwiatkowska KM; Durso DF; Ivanchenko M; Monti D; Lodi R; Franceschi C; Cortelli P; Garagnani P; Bacalini MG

A Meta-Analysis of Brain DNA Methylation Across Sex, Age, and Alzheimer's Disease Points for Accelerated Epigenetic Aging in Neurodegeneration Journal Article

In: Frontiers in aging neuroscience, 13 , pp. 639428, 2021.

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Nato G; Corti A; Parmigiani E; Jachetti E; Lecis D; Colombo MP; Delia D; Buffo A; Magrassi L

Immune-tolerance to human iPS-derived neural progenitors xenografted into the immature cerebellum is overridden by species-specific differences in differentiation timing Journal Article

In: Scientific reports, 11 (1), pp. 651, 2021.

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Morsiani C; Terlecki-Zaniewicz L; Skalicky S; Bacalini MG; Collura S; Conte M; Sevini F; Garagnani P; Salvioli S; Hackl M; Grillari J; Franceschi C; Capri M

Circulating miR-19a-3p and miR-19b-3p characterize the human aging process and their isomiRs associate with healthy status at extreme ages Journal Article

In: Aging Cell, 20 (7), pp. e13409, 2021, ISBN: 10.1111/acel.13409.

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Klionsky DJ; Abdel-Aziz AK; Abdelfatah S; ....; Scovassi AI; et al.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) Journal Article

In: Autophagy, 17 (1), pp. 1-382, 2021.

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Chiodi I; Perini C; Berardi D; Mondello C

Asparagine sustains cellular proliferation and c‑Myc expression in glutamine‑starved cancer cells Journal Article

In: Oncology reports, 45 (6), pp. 96, 2021.

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Bacalini MG; Gentilini D; Monti D; Garagnani P; Mari D; Cesari M; Ogliari G; Passarino G; Franceschi C; Pirazzini C; Arosio B

No association between frailty index and epigenetic clocks in Italian semi-supercentenarians Journal Article

In: Mechanisms of ageing and development, 197 , pp. 111514, 2021.

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Morello G; Cancila V; La Rosa M; Germano G; Lecis D; Amodio V; Zanardi F; Iannelli F; Greco D; La Paglia L; Fiannaca A; Urso AM; Graziano G; Ferrari F; Pupa SM; Sangaletti S; Chiodoni C; Pruneri G; Bardelli A; Colombo MP; Tripodo C

T Cells Expressing Receptor Recombination/Revision Machinery Are Detected in the Tumor Microenvironment and Expanded in Genomically Over-unstable Models Journal Article

In: Cancer immunology research, 2021.

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Scalera C; Ticli G; Dutto I; Cazzalini O; Stivala LA; Prosperi E

Transcriptional stress induces chromatin relocation of the nucleotide excision repair factor XPG Journal Article

In: International journal of molecular sciences, 22 , pp. 6589, 2021.

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Silva B; Arora R; Bione S; Azzalin CM

TERRA transcription destabilizes telomere integrity to initiate break-induced replication in human ALT cells. Journal Article

In: Nature communications, 12 (1), pp. 3760, 2021.

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Lombardi A; Arseni L; Carriero R; Compe E; Botta E; Ferri D; Uggè M; Biamonti G; Peverali FA; Bione S; Orioli D

Reduced levels of prostaglandin I 2 synthase: a distinctive feature of the cancer-free trichothiodystrophy Journal Article

In: Proceedings of the National Academy of Sciences of the United States of America., 118 (26), 2021.

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Guardamagna I; Bassi E; Savio M; Perucca P; Cazzalini O; Prosperi E; Stivala LA

A functional in vitro cell-free system for studying DNA repair in isolated nuclei Journal Article

In: Journal of cell science, 133 (11), 2021.

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598 entries « 1 of 15 »