Scolari Francesca
Istituto di Genetica Molecolare “Luigi Luca Cavalli-Sforza”
c/o Dipartimento di Biologia e Biotecnologie
Università di Pavia 
Via Ferrata, 9 – 27100 PAVIA
tel: +39 0382 986421

Curriculum vitaeDownload

List of publicationsDownload

Research Activities

My research activity aims at unraveling the genomic, molecular and physiological bases of the biology of insects of public health and agricultural importance to expand knowledge and develop new tools for their control. My contributions to science can be summarized as follows:

  • Study of the co-evolution between insects, endosymbionts and viruses integrating genomics, transcriptomics and metabolomics. My research focuses on investigating the relationships between endosymbionts and insect hosts and their impact on insect fitness and vector capacity.
  • Functional genomics of insect reproduction. This research aims at identifying the composition, regulation and function of insect seminal fluid to expand knowledge and identify novel targets to manipulate the reproductive capacity of agricultural pests and disease vectors.
  • Insect-plant interaction at the functional genomics, physiological and behavioural level. This research focuses on the identification and functional analysis of chemosensory genes and proteins in agricultural pests.

Recent publications


Croce AC; Garbelli A; Moyano A; Soldano S; Tejeda-Guzman C; Missirlis F; Scolari F

Developmental and Nutritional Dynamics of Malpighian Tubule Autofluorescence in the Asian Tiger Mosquito Aedes albopictus Journal Article

In: International journal of molecular sciences, vol. 25, iss. 1, pp. 245, 2024.

Abstract | Links | BibTeX


Croce AC; Scolari F

Characterization of Spontaneous Melanization by Fluorescence Spectroscopy: A Basis for Analytical Application to Biological Substrates Journal Article

In: Biology-Basel, vol. 12, iss. 3, pp. 433, 2023.

Abstract | Links | BibTeX

Faris P; Negri S; Faris D; Scolari F; Montagna D; Moccia F

Hydrogen Sulfide (H2S): As A Potent Modulator And Therapeutic Prodrug In Cancer Journal Article

In: Current medicinal chemistry, vol. 30, iss. 40, pp. 4506-4532, 2023.

Abstract | Links | BibTeX

Attardo GM; Benoit JB; Michalkova V; Kondragunta A; Baumann AA; Weiss BL; Malacrida A; Scolari F; Aksoy S

Lipid metabolism dysfunction following symbiont elimination is linked to altered Kennedy pathway homeostasis Journal Article

In: iScience, vol. 26, iss. 7, pp. 107108, 2023.

Abstract | Links | BibTeX

Moyano A; Croce AC; Scolari F

Pathogen-Mediated Alterations of Insect Chemical Communication: From Pheromones to Behavior Journal Article

In: Pathogens, vol. 12, iss. 11, pp. 1350, 2023.

Abstract | Links | BibTeX


Croce AC; Scolari F

Autofluorescent Biomolecules in Diptera: From Structure to Metabolism and Behavior Journal Article

In: Molecules, vol. 27, iss. 14, pp. 4458, 2022.

Abstract | Links | BibTeX

Scolari F; Khamis FM; Perez-Staples D

Editorial: Novel Insights Into Female Post-Mating Physiology in Insects Journal Article

In: Frontiers in physiology, vol. 13, pp. 877222, 2022.

Links | BibTeX

Negri S; Scolari F; Vismara M; Brunetti V; Faris P; Terribile G; Sancini G; Berra-Romani R; Moccia F

GABAA and GABAB Receptors Mediate GABA-Induced Intracellular Ca2+ Signals in Human Brain Microvascular Endothelial Cells Journal Article

In: Cells, vol. 11, iss. 23, pp. 3860, 2022.

Abstract | Links | BibTeX

Scolari F; Girella A; Croce AC

Imaging and spectral analysis of autofluorescence patterns in larval head structures of mosquito vectors Journal Article

In: European journal of histochemistry, vol. 66, iss. 4, pp. 3462, 2022.

Abstract | Links | BibTeX

Vismara M; Negri S; Scolari F; Brunetti V; Trivigno SMG; Faris P; Galgano L; Soda T; Berra-Romani R; Canobbio I; Torti M; Guidetti GF; Moccia F

Platelet-Derived Extracellular Vesicles Stimulate Migration through Partial Remodelling of the Ca2+ Handling Machinery in MDA-MB-231 Breast Cancer Cells Journal Article

In: Cells, vol. 11, iss. 19, pp. 3120, 2022.

Abstract | Links | BibTeX

Croce AC; Scolari F

The Bright Side of the Tiger: Autofluorescence Patterns in Aedes albopictus (Diptera, Culicidae) Male and Female Mosquitoes. Journal Article

In: Molecules, vol. 27, iss. 3, pp. 713, 2022.

Abstract | Links | BibTeX


Scolari F; Khamis FM; Perez-Staples D

Beyond Sperm and Male Accessory Gland Proteins: Exploring Insect Reproductive Metabolomes Journal Article

In: Frontiers in physiology, vol. 12, no. 1, pp. Frontiers in physiology, 2021.

Abstract | Links | BibTeX

Serra NS; Garrido CM; Català AB; Tait G; Merli D; Carlin S; Malacrida AR; Gasperi G; Anfora G; Scolari F

Electrophysiological Responses of the Mediterranean Fruit Fly, Ceratitis capitata, to the Cera Trap® Lure: Exploring Released Antennally-Active Compounds Journal Article

In: Journal of chemical ecology, vol. 47, iss. 3, no. 265, pp. 279, 2021.

Abstract | Links | BibTeX

Scolari F; Sandionigi A; Carlassara M; Bruno A; Casiraghi M; Bonizzoni M

Exploring Changes in the Microbiota of Aedes albopictus: Comparison Among Breeding Site Water, Larvae, and Adults. Journal Article

In: Frontiers in microbiology, vol. 12, pp. 624170, 2021.

Abstract | Links | BibTeX

Scolari F; Valerio F; Benelli G; Papadopoulos NT; Vaníckova' L.

Tephritid Fruit Fly Semiochemicals: Current Knowledge and Future Perspectives Journal Article

In: Insects, vol. 12, no. 5, 2021.

Abstract | Links | BibTeX

Savini G; Scolari F; Ometto L; Rota-Stabelli O; Carraretto D; Gomulski LM; Gasperi G; Abd-Alla AMM; Aksoy S; Attardo GM; Malacrida AR

Viviparity and habitat restrictions may influence the evolution of male reproductive genes in tsetse fly (Glossina) species Journal Article

In: BMC biology, vol. 19, no. 1, 2021.

Abstract | Links | BibTeX


Attardo GM; Scolari F; Malacrida A

Bacterial Symbionts of Tsetse Flies: Relationships and Functional Interactions Between Tsetse Flies and Their Symbionts Journal Article

In: Results and problems in cell differentiation, vol. 69, pp. 497-536, 2020.

Abstract | Links | BibTeX

Carraretto D; Aketarawong N; Di Cosimo A; Manni M; Scolari F; Valerio F; Malacrida AR; Gomulski LM; Gasperi G

Transcribed sex-specific markers on the Y chromosome of the Oriental fruit fly, Bactrocera dorsalis. Journal Article

In: BMC Genetics, vol. 21, no. Suppl. 2, pp. 125, 2020.

Links | BibTeX


Scolari F; Casiraghi M; Bonizzoni M

Aedes spp. and Their Microbiota: A Review Journal Article

In: Frontiers in microbiology, vol. 10, pp. 2036, 2019.

Abstract | Links | BibTeX

Attardo GM; Abd-Alla AMM; Acosta-Serrano A; Allen JE; Bateta R; Benoit JB; Bourtzis K; Caers J; Caljon G; Christensen MB; Farrow DW; Friedrich M; Hua-Van A; Jennings EC; Larkin DM; Lawson D; Lehane MJ; Lenis VP; Lowy-Gallego E; Macharia RW; Malacrida AR; Marco HG; Masiga D; Maslen GL; Matetovici I; Meisel RP; Meki I; Michalkova V; Miller WJ; Minx P; Mireji PO; Ometto L; Parker AG; Rio R; Rose C; Rosendale AJ; Rota-Stabelli O; Savini G; Schoofs L; Scolari F; Swain MT; Takac P; Tomlinson C; Tsiamis G; Van Den Abbeele J; Vigneron A; Wang J; Warren WC; Waterhouse RM; Weirauch MT; Weiss BL; Wilson RK; Zhao X; Aksoy S

Comparative genomic analysis of six Glossina genomes, vectors of African trypanosomes Journal Article

In: Genome biology, vol. 20, no. 1, pp. 187, 2019.

Abstract | Links | BibTeX

Pischedda E; Scolari F; Valerio F; Carballar-Lejarazu R; Catapano PL; Waterhouse RM; Bonizzoni M.

Insights Into an Unexplored Component of the Mosquito Repeatome: Distribution and Variability of Viral Sequences Integrated Into the Genome of the Arboviral Vector Aedes albopictus Journal Article

In: Frontiers in genetics, vol. 10, pp. 93, 2019.

Abstract | Links | BibTeX

Meccariello A; Salvemini M; Primo P; Hall B; Koskinioti P; Dalíková M; Gravina A; Gucciardino MA; Forlenza F; Gregoriou ME; Ippolito D; Monti SM; Petrella V; Perrotta MM; Schmeing S; Ruggiero A; Scolari F; Giordano E; Tsoumani KT; Marec F; Windbichler N; Arunkumar KP; Bourtzis K; Mathiopoulos KD; Ragoussis J; Vitagliano L; Tu Z; Papathanos PA; Robinson MD; Saccone G

Maleness-on-the-Y ( MoY) orchestrates male sex determination in major agricultural fruit fly pests Journal Article

In: Science, vol. 365, no. 6460, pp. 1457-1460, 2019.

Abstract | Links | BibTeX

Falchetto M; Ciossani G; Scolari F; Di Cosimo A; Nenci S; Field LM; Mattevi A; Zhou JJ; Gasperi G; Forneris F

Structural and biochemical evaluation of Ceratitis capitata odorant-binding protein 22 affinity for odorants involved in intersex communication Journal Article

In: Insect molecular biology, vol. 28, no. 3, pp. 431-443, 2019.

Abstract | Links | BibTeX


Merli D; Mannucci B; Bassetti F; Corana F; Falchetto M; Malacrida AR; Gasperi G; Scolari F

Larval Diet Affects Male Pheromone Blend in a Laboratory Strain of the Medfly, Ceratitis capitata (Diptera: Tephritidae) Journal Article

In: Journal of chemical ecology, vol. 44, no. 4, pp. 339-353, 2018.

Abstract | Links | BibTeX

Scolari F; Attardo GM; Aksoy E; Savini G; Abd-Alla A; Aksoy S; Malacrida AR

Symbiotic microbes affect the expression of male reproductive genes in Glossina m. morsitans Journal Article

In: BMC microbiology, vol. 18, no. Suppl 1, pp. 169, 2018.

Abstract | Links | BibTeX

Gomulski LM; Mariconti M; Di Cosimo A; Scolari F; Manni M; Savini G; Malacrida AR; Gasperi G.

The Nix locus on the male-specific homologue of chromosome 1 in Aedes albopictus is a strong candidate for a male-determining factor Journal Article

In: Parasites & vectors, vol. 11, no. (Suppl 2), pp. 647, 2018.

Abstract | Links | BibTeX


Manni M; Guglielmino CR; Scolari F; Vega-Rúa A; Failloux AB; Somboon P; Lisa A; Savini G; Bonizzoni M; Gomulski LM; Malacrida AR; Gasperi G

Genetic evidence for a worldwide chaotic dispersion pattern of the arbovirus vector, Aedes albopictus. Journal Article

In: PLoS neglected tropical diseases, vol. 11, no. 1, pp. e0005332, 2017.

Abstract | Links | BibTeX