IGM-GUEST SEMINAR SERIES: Andrea Ciliberto

Why are tubulins different?

Andrea Ciliberto, PhD

IFOM – Istituto Fondazione di Oncologia Molecolare ETS

 

When: 12.00-1 pm, Wednesday, October 23st 2024
Where: Aula Falaschi, Ground floor, Institute of Molecular Genetics  Via Abbiategrasso 207, Pavia
(Entrance in Via Ferrata 9, Campus “La Nave”, University of Pavia

IGM Guest Seminars – M di Antonio

Individual G-quadruplex targeting with chemically functionalised CRISPR-Cas9 uncovers ligand-specific biological responses

 

Marco di Antonio, PhD

Imperial College London, Department of Chemistry, London, UK

When: 12.00-1 pm, Monday, October 21st 2024
Where: Aula Falaschi, Ground floor, Institute of Molecular Genetics  Via Abbiategrasso 207, Pavia
(Entrance in Via Ferrata 9, Campus “La Nave”, University of Pavia)

Sammy Basso and IGM

IGM colleagues remember Sammy Basso, a brilliant researcher, a friend, a guide in our work.

Sammy had a love of life and was always friendly, ironic and cheerful. We will continue studying progeria with Sammy’s enthusiasm, being even more motivated by the influence he had on each of us . Thank you Sammy!

Spoke 6: RNA drug development 8th veRNAdì

External Seminars@IGM-Jeremy Borniger

Wednesday, March 6th, 2024, at 3 pm (CET),

Dr. Jeremy C. Borniger

Assistant Professor at Cold spring Harbour Laboratory (US)

will be presenting a seminar titled:“Neuronal circuit basis for glucocorticoid circadian rhythm disruption in breast cancer”To join the seminar, please use the following Teams link:https://teams.microsoft.com/l/meetup-join/19%3ameeting_MDQxNWQyZjUtNzNkNS00NGJlLThlMTMtYzVjMWJjNTVmN2Q5%40thread.v2/0?context=%7b%22Tid%22%3a%2234c64e9f-d27f-4edd-a1f0-1397f0c84f94%22%2c%22Oid%22%3a%221503aa2f-fb68-4453-8463-7eedfff33201%22%7d

Sara Tavella CNR DSB Prize

CNR-IGM, Istituto di Genetica Molecolare “Luigi Luca Cavalli Sforza” is proud to announce that Sara Tavella was awarded with the DSB 2023 Scientific Prize for the research topic entitled: “Molecular, cellular, immunological and epidemiological aspects of the #SARS-#CoV2 #infection”.

Genome Integrity Webinar series

A virtual forum organized by GiiN
Winter Spring 2024 – Seminars Calendar:
From 5 to 6PM Rome, ZOOM link: https://uniroma1.zoom.us/j/95149984403

Calendar 2024

For more information contact or visit:
Twitter: GenomeIINetwork
GenomeIntegrityItaly@gmail.com
https://genomeintegrityita.wixsite.com/giin

Telomeres as a target of a potential innovative therapy for the 10-15% of intractable tumors

A possible therapeutic solution for treating ALT tumors has been identified in the IFOM laboratories, which include for example glioblastoma and osteosarcoma and against which chemotherapy and radiotherapy are not very effective. It is a therapy based on Antisense Oligonucleotides that acts on RNAs that promote the longevity of cancer cells of this type of tumor. The study, recently published in Nature Communications, was supported by the AIRC Foundation.

Ilaria Rosso, Corey Jones-Weinert, Francesca Rossiello, Matteo Cabrini, Silvia Brambillasca, Leonel Munoz-Sagredo, Zeno Lavagnino, Emanuele Martini, Enzo Tedone, Massimiliano Garre’, Julio Aguado, Dario Parazzoli, Marina Mione, Jerry W. Shay, Ciro Mercurio & Fabrizio d’Adda di Fagagna
Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAs
Nat Commun. 2023 Nov 4;14(1):7086. doi: 10.1038/s41467-023-42831-0